New Cannabis Club

Antibiotic Uses Of Cannabis.

In the past twenty years in western medication, marijuana has been allotted antibiotic activity ; as a consequence, one or two studies in relation to this probability have been undertaken. H. B. M. Murphy ( 1963 : twenty ) reported inquiries in Eastern Europe. He said that it is purported to be useful against gram positive organisms at one / 100,000 dilution, but to be largely inactivated by plasma, so that prospects for its use seem to be, limited to E. N. T. ( ear, nose and throat ) and skin diseases.

Dr. J. Kabelikovi ( 1952 : 500-503 ) and his colleagues carried out tests on rats, which were like tests carried out with penicillin in vitro. The alcohol extraction of cannabis was bacterially effective against many gram-positive and one gram-negative microbes.
It was also discovered that a paste sort of external application was successful. According to Kabelikovi, from a study of two thousand herbs by Czechoslovakian scientists it was discovered that Cannabis indica ( the Indian Hemp ) was the most promising in the field of antibiotics. In a 1959 publication of Pharmacie, Krejci stated : From the flourishing tips and leaves of hemp, Cannabis sativa var indica bred in Middle Europe, were removed a phenol and an acid fragment.

From the acid fraction, 2 acids were got, of which one saved its antibiotic properties ( p.349 ). In another Czechoslovakian publication, Krejci ( 1961 : 1351-1353 ) referred to 2 further samples with antibiotic activity.

The outcome of tests lead us to realize that the antibacterial action of Cannabis sativa isn’t matching to the hashish effect found, as an example, in tetrahydrocannabinol. it was established that Cannabis sativa is effective as an antibiotic for local infections. Kabelik, Krejci, and Santavy ( 1960 : thirteen ) include in cannabis as a Medicant the varied micro-organisms against which cannabis is effective. Evidence might be furnished that the cannabis extracts produce an exceedingly sufficient antibacterial effect on the following microbes : staphylococcus pyogenes aureus, steptococcus alpha haemolyticus, streptococcus beta haemolyticus, enterococcus, diplococcus pneumonia, B. Anthracis, and corynebacterium diptheriae i.e, each one of them gram-positive micro-organisms. Notable is the effect on staphylococcus aureaus strains, which are immune to penicillin and to other antibiotics. These writers also discussed that E. Coli ( gramnegative bacteria ) were tested and revealed to be proof against the cannabis extract. One of the conclusions was the chance of employing the antibiotics domestically without any danger of manufacturing resistant strains to other antibiotics administered at the same time through treatment ( Kabelik, et al, 1960 : thirteen ). Veliky and Genest in Suspension Culture of Cannabis Sativa, reported the ethanol extraction of cultured cells exhibited antibiotic activity against Germ megatherium, staphlococcus aureaus and escherichia coli ( p. 493 ). Other reports claimed a told antibiotic effect has been noted in South America, where fresh leaves, after being ground, are used as a bandage for furuncles, and in folks medication in Europe for treatment of erysipelas ( Kabelik, et al, 1960 : eight ).

Antibiotics Conclusion.

This section on the antibiotic uses of cannabis concludes with an outline of several reports from varied states.
In Pharmacopee Arabe : The ground-up seeds are combined with bread for folks with tuberculosis ( Andrews and Vinkenoog, 1967 : 145 ).
In Czechoslovakia : A preparation from seed pulp was introduced by Sirek to act as a roborant diet in treatment of tuberculosis ( Kabelik, 1960 : eight ).
In Southern Rhodesia : The plant is employed as an African cure for malaria, anthrax, sepsis, black water fever, dysentery, blood-poisoning, tropical quinine-malarial haemoglobinuria, and a wart drugs ( Watt, 1961 : 13 ).
In Argentina : Cannabis is regarded as a real cure for tetanus, colic, gastralgia, swelling of the liver, gonorrhea, sterility, impotency, abortion, tuberculosis of the lungs and asthma, even the root-bark has been picked up in spring, and employed as a febrifuge, tonic, for treatment of dysentery and gastralgia, either pulverized or in type of decoctions.
The root when ground and applied to burns is said to alleviate agony. Oil from the seeds has been often used even in treatment of cancer. ( Kabelik, 1960 : eight ).

The results of THC On Epileptic Youngsters . In 1949, Davis and Ramsey reported a study of the consequences of THC on epileptic youngsters. The demonstration of anticonvulsant activity of the tetrahydrocannabinol ( THC ) congeners by lab tests ( Loewe and Goodman, Federation Proc, 6 : 3521 1947 ) pushed trial in 5 institutionalized epileptic youngsters ( David and Ramsey, 1949 : 284-285 ). Of these 5 youngsters, all had harsh demonstrative grand mal epilepsy with psychological retardation ; 3 also had cerebral palsy ; and 3 had focal fit activity. The EEG tracings were reported to be way aberrant in all 5 youngsters. The results after being treated with homologues of THC, were reported as follows : 3 children-responded at least as well as to prior treatment. 4th child-almost absolutely episode free. 5th child-entirely fit free. As a consequence of their study, David and Ramsey ( 1949 : 284-285 ) felt the cannabinols herein reported merit further trial in non-institutionalized epileptics.
Dr. Vansim of Edgewood armoury wrote in a latterly printed book Psychotomimetic Drugs, the man-made preparations of cannabis are of interest. There are 3 areas where they might be of definite use in medication ( Efron, 1969 : 333-334 ).

One concerns the employment of a cannabis analogue which Dr. Walter S. Loewe reported extremely impressive in forestalling grand mal episodes if given in tiny doses. The second use pertains to cannabis as a mood depressant.

Straub ( Walton, 1938 : three ), Adams ( 1942 : 726-727 ), and Stockings ( 1947, 920-922 ) point at the possible use of cannabis and cannabis analogues in relieving dysphoria in depressed patients. Other writers ( Parker and Wrigley, 1950 : 278-279 ) had smaller success but advocated further research in this field. A dispatch from London in 1968 endorses that cannabis treats the symptoms and not the cause by focusing the user’s attention on his stresses and pains without helping him to solve them ( Report by the Advisory Council , 1968 : eleven ). The 3rd use is described by Douthwaite, who used hashish in 1947 for reducing of foreboding and strain in patients with duodenal ulcer ( Pool , 1948 : 279 ).
A dispatch in a 1965 issue of Medical Stories ( Cardiac Glycocides, p. Six ) counsels cannabis as treatment for a particular kind of malignancy. Cannabis is acknowledged as an appetite stimulant, which means that the drug could be helpful in the treating of pathological loss of appetite known as anorexia nervosa ( Grinspoon, 1969 : twenty-one ). Similar symptoms exist in terminal cancer patients who, when treated with cannabis over a short period, demonstrated kick of appetite, euphoria, heightened sense of contentment, mild analgesia and an indifference to agony which reduced the requirement for opiates ( DHEW, 1971 : 11 ). Cannabis has been latterly suggested as an accessory in the treatment of alcoholics and drug abusers. Roger Adams ( 1942 : 726-727 ) and Todd Mikuriya ( 1970a : 187-191 ) noted the substitution of smoked cannabis for alcohol could have rehabilitative price for certain alcoholics. Marijuana as a Treatment Of Withdrawal. Relating to the utilization of cannabis analogue in the treating of drug, alcohol and depressive state withdrawal, Thompson and Proctor ( 1953 : 520523 ) report the following : Depressive States.

Twenty cases of mental depression-4 improved ( twenty percent ) six cases of insane depression-none improved ( 00% )
Post-Alcoholic Cases.
70 cases–59 reported clinical lessening of symptoms ( 84% )

Drug Cases.
Six cases of barbiturate addiction-4 reported amelioration of symptoms ( 66% ) four cases of dilaudid addiction-3 reported easing ( seventy five percent ) two cases of pantopan and one paregoric addiction-all reported smooth withdrawal ( 100 percent ) twelve cases of Demerol addiction-10 withdrawals in one week ( 83% ) 6 cases of morphine addiction-2 withdrawals without upsetting symptoms ( 33% ) Conclusions. The doctors concluded that Pyrahexyl ( a manmade cannabis-like drug ) and related compounds are constructive in the treatment of withdrawal pains from the utilization of alcohol to a marked degree, and in the handling of withdrawal problems from the use of opiates to a less marked, but still important degree ( Thompson & Proctor, 1953:520-523 ). Drs. Allentuck and Bowman undertook a study of the utilization of marijuana in the morphine avoidance syndrome. They stated : a sequence of cases were chosen from among cokeheads having treatment, Comparative results were chartered for the gradual withdrawal, total withdrawal, and marijuana derivative substitution, as techniques of treatment, 49 subjects were studied. The results in general, though still inconclusive, suggest the marijuana substitution methodology ameliorated or eliminated ( the symptoms ) earlier, the patient was in a better mindset, his spirits raised, his physical condition was more speedily rehabilitated, and he voiced a requirement to resume his occupation earlier ( p. Two hundred and fifty ).

Mayor LaGuardia’s Council On Marijuana.

In his study of the medical application of cannabis for Mayor LaGuardia’s board, Dr. Samuel Allentuck reported favorable leads to treating withdrawal of opiate addicts with tetrahydrocannabinol ( THC ), a powerful purified product of the hemp plants ( Mikuriya, 1969 : 38 ). Roger Adams’ detailed studies, as reported by Dr. C. K. Himmelsbach in his 1944 article Treatment of the Morphine avoidance Syndrome with a Manmade Cannabis-Like Compound ( 1944:26 ), indicated that withdrawal manifestations were said to be mild.

The reported healing worth of marijuana was traced to improved appetite, larger sleep, euphoria, and a reduction of the force or elimination of avoidance phenomena.
Himmelsbach had smaller success when he scanned the effect of a pyrahexyl compound on the morphine avoidance syndrome, as noted by his conclusions that : Pyrahexyl compound seems to possess considerable cannabis-like effect when administered orally, but tiny or none when given intramuscularly. When given by mouth In definitely effective amounts pyrahexyl compound had no discernible ameliorative effect on the opiate avoidance syndrome ( P. Twenty-nine ). The NY City Mayor LaGuardia’s Panel on marijuana ( 1944 : 147-148 ) reported two possible healing applications of marijuana : the 1st is the everyday euphoria-producing action which might be applicable in the treating of diverse sorts of psychological depression ; the second is the rather unique property which ends in the invigoration of appetite.

In the light of this proof and in view of the undeniable fact that there’s an absence of any significant Indication of reliance on the drug, It was reasoned that marijuana could be handy in assuaging the withdrawal problems in cokeheads. the studies here described weren’t adequately complete to create the value of such treatment. A study was then undertaken at Riker’s Island ( N.Y. ) Prison concerning fifty six morphine or heroin hooked inmates. 2 groups were similarly matched according to age, physical condition, length and magnitude of habit, and so on. One group received no treatment or Magendie’s solution, and the other received fifteen mg. Of THC and / or pill. The impression was gained that those that received tetrahydrocannabinol had less serious withdrawal problems than those who received no treatment or who were treated with Magendie’s solution the report said. the report also said this purported healing use of marijuana should be analyzed under utterly controlled conditions before significant conclusions can be developed ( NY City Mayor, AU : 147-148 ).

Work Pains.

Some reports indicate that cannabis helps relieve work pains. Such uses are reported among local clans in South Africa and Southern Rhodesia : The Suto clan fumigates the parturient girl to alleviate pain;the Sotho ladies of Basutoland are reported as smoking cannabis to stupefy themselves during birth, and have also been known to administer the ground-up achene with bread or mealiepap to a kid during weaning ( Watt, 1962:13 ).

Leprosy.

The employment of cannabis in the treating of leprosy has been described in a 1939 compendium of Malayan medication : Seeds of Hydnocarpus anthelmintim … Form the basis of the Tai Foon Chee treatment of leprosy. After squashing and sieving, they’re combined with Cannabis indica in the percentage of 2 parts of the seeds to one of Indian hemp ( Andrews and Vinkenoog, 1967 : 146 ). Similarly , Watt and Breyer-Brandwijk quote Pappe the early colonist employed a decoction in the treating of prolonged cutaneous eruptions, most likely in leprosy ( Andrews and Vinkenoog, 1967 : 146 ).
Kabelik, Krejci, and Santavy have reported favorable ends in stornatitis aphtosa, gingivitis, and in paradentoses with a mouthwash made of cannabis ( Kabelik et al, 1960 : 13 ).
In connection with the utilization of cannabis, Chopra and Chopra ( 1957 : 12-13 ) listed some preparations employed in the practice of native medicine in India in 1957. They summarize their article the employment of the Cannabis Drugs in India ( 1957 : 12-13 ) by pronouncing
. With respect to the utilization of cannabis in Indian native medication at the current time, it could be asserted that this was and still is fairly at length utilized in both the Ayurvedle ( Hindu ) and Tibbi ( Mohammedan ) techniques of drugs as an anodyne, hypnotic, analgesic and antispasmodic, and as a cure for external application to piles. It’s also employed in the handling of dysmennorhoea, rheumatism, prolonged runs of the sprue type, gonorrhea, malaria and psychological illnesses on the recommendation of itinerant followers of Native drugs as well as quacks who wander about the country. For medical purposes the drug is administered by mouth and very rarely by smoking.

Cannabis In Native Drugs .

The employment of Cannabis drugs in native medication has greatly fell during recent times for 2 reasons. Firs, thanks to the quick degradation of the potency of cannabis drugs in storage, the examples available on the market being regularly inactive and quite worthless.
Second , because a number of powerful and effective drugs of the type utilized in western medication are presently available on the market and are used quite at length by the followers of native drugs in the place of cannabis, for the anodyne, sedative and hypnotic effects. In the rustic areas of India the disciples of native medication still use cannabis quite extensively In their practice. The same article lists a selection of uses in which cannabis is used therapeutically in veterinary drugs.
Dr. R. N. Chopra ( 1940 : 361 ) reports the following medical household uses of Indian Hemp : The hemp drugs are generally used as household cures in the amelioration of many minor infirmities.
A mild libation made of Bhang leaves is said to sharpen appetite and to help digestion. Indian hemp is frequently used as a smoke and as a drink for its supposed prophylactic worth against marijuana in malarious tracts. Bhang drinks form one of the popular household cures for gonorrhea and dysuria. On account of their mild diuretic and sedative properties these drinks likely give a specific quantity of evidential relief. Similarly , the utilization of Bhang for dysmenorrhea, asthma, and other spasmodic conditions isn’t unusual. A bandage made of fresh leaves is a typical household cure for agonizing affections of the eyes, conjunctivitis, distended joints, orchitis, and other acute inflammatory conditions. Tuberculosis, Anthrax, Tetanus, And Menstrual Cramps Tuberculosis, anthrax, tetanus, and menstrual cramps are among the varied medical uses of Cannabis reported. Reports from Mexico indicate the utilization of marijuana smoking to chill and to endure heat and fatigue ( Mikuriya, 1969 : 37 ). Kabelik et al. ( 1960 : thirteen ) also debate other sundry uses of cannabis.
In human care the most satisfactory results have been got with the following medicaments mixed with substances obtained from cannabis : dusting powder along with boric acid ( otitis ), cream ( staphylococcus infected injuries, staphylodermia and so on ), ear drops ( otitis chron. ), alcohol solutions with glycerin ( treatment of rhagades on the nipples of nursing women-prevention of staphylococcic mastitis, ) aqueous emulsions ( sinusitis ), dentin powder with the IRC ( Isolated Resin from Cannabis ) ( caries ).

The preparations discussed above have been already tested scientifically, and will at last be supplied for production. The experiments made in clinical practice, especially in stomatology, otorhinolaryngology, gynecology, dermatology, physiology, with some pharmaceutical preparations containing antibacterial substances from cannabis have been reported.
Attention has been drawn towards the beneficial function of the active substances from cannabis in veterinary drugs, and especially in preventative drugs for anthropozoonoses. Murphy ( 1963 : twenty ) makes reference to a report by Lang, Treatment of Acute Appendicitis with a mix of Ma Jen, which asserts the drug has allegedly been utilized in China for the handling of appendicitis. The Xosa clan in S. A. employs it for treatment of soreness of the feet ( Kabelik et al, 1960 : seven ), while the Mfengu and Hottentot use the plant as a snake-bite cure ( Watt, 1962 : thirteen ). Headache , Facial Neuralgia, And Sexual Stimulant Other healing uses ascribed to marijuana are for the handling of migraines, as a drug, and as a hypnotic. Hollister ( 1971 : twenty-eight ) said that other uses which have been suggested for marijuana include the handling of epilepsy, as prophylaxis for attacks of headache or facial neuralgia, or as a sexual stimulant.